MRCOG Part 1 – Pharmacology

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Question 1 of 63

1. Question

What is the mechanism of action of the combined oral contraceptive pill?

Inhibition of fertilization
Correct Incorrect Correct answer

Inhibition of implantation
Correct Incorrect Correct answer

Inhibition of ovulation
Correct Incorrect Correct answer

Thickening of cervical mucus
Correct Incorrect Correct answer

Thinning of endometrium
Correct Incorrect Correct answer

Correct

Incorrect

Question 2 of 63

2. Question

Which of the following is not a side effect of antimuscarinic treatment for overactive bladder?

Excessive salivation
Correct Incorrect Correct answer

Photophobia
Correct Incorrect Correct answer

Tachycardia
Correct Incorrect Correct answer

Visual disturbances
Correct Incorrect Correct answer

Urinary retention
Correct Incorrect Correct answer

Correct

Incorrect

Question 3 of 63

3. Question

Which of the following is not a side effect of the combined oral contraceptive pill?

Acne
Correct Incorrect Correct answer

Breast tenderness
Correct Incorrect Correct answer

Melasma
Correct Incorrect Correct answer

Unscheduled bleeding
Correct Incorrect Correct answer

Weight gain
Correct Incorrect Correct answer

Correct

Incorrect

Question 4 of 63

4. Question

Which of the following is not an absolute contraindication to the combined oral contraceptive pill?

BRCA1 gene mutation
Correct Incorrect Correct answer

Current venous thromboembolism
Correct Incorrect Correct answer

Factor V Leiden mutation
Correct Incorrect Correct answer

History of migraine with aura
Correct Incorrect Correct answer

Previous transient ischaemic attack
Correct Incorrect Correct answer

Correct

Incorrect

Question 5 of 63

5. Question

Which of the following is a relative contraindication to combined oral contraceptive pill?

Age of 40 and smoker of 10 cigarettes per day
Correct Incorrect Correct answer

BMI of 30 kg/m2
Correct Incorrect Correct answer

Factor V Leiden mutation
Correct Incorrect Correct answer

Hypertension with BP 140/95 mmHg
Correct Incorrect Correct answer

Liver adenoma
Correct Incorrect Correct answer

Correct

Incorrect

Question 6 of 63

6. Question

Which of the following statements regarding use of the combined oral contraceptive pill (COCP) and venous thromboembolism (VTE) is incorrect?

COCP use is associated with an increased risk of VTE compared to non-users
Correct Incorrect Correct answer

The risk of VTE is highest in the first few months of starting the COCP
Correct Incorrect Correct answer

The risk of VTE returns to normal within one year of stopping the COCP
Correct Incorrect Correct answer

The type of progestogen in the COCP influences the risk of VTE
Correct Incorrect Correct answer

Use of a COCP containing co-cyprindiol is associated with a higher risk of VTE than one containing levonorgestrel
Correct Incorrect Correct answer

Correct

Incorrect

Question 7 of 63

7. Question

Which of the following medications does not affect the metabolism and efficacy of the combined oral contraceptive pill?

Griseofulvin
Correct Incorrect Correct answer

Ketoconazole
Correct Incorrect Correct answer

Phenytoin
Correct Incorrect Correct answer

Rifampicin
Correct Incorrect Correct answer

Ritonavir
Correct Incorrect Correct answer

Correct

Incorrect

Question 8 of 63

8. Question

What is the mechanism of action of the progestogen-only pill?

Inhibition of fertilization
Correct Incorrect Correct answer

Inhibition of implantation
Correct Incorrect Correct answer

Inhibition of ovulation
Correct Incorrect Correct answer

Thickening of cervical mucus
Correct Incorrect Correct answer

Thinning of endometrium
Correct Incorrect Correct answer

Correct

Incorrect

Question 9 of 63

9. Question

Which of the following is a side effect of the progestogen-only pill?

Depression
Correct Incorrect Correct answer

Headache
Correct Incorrect Correct answer

Irregular menstrual bleeding
Correct Incorrect Correct answer

Weight gain
Correct Incorrect Correct answer

Weight loss
Correct Incorrect Correct answer

Correct

Incorrect

Question 10 of 63

10. Question

Which of the following is an absolute contraindication to the progestogen-only pill?

Current breast cancer
Correct Incorrect Correct answer

Decompensated liver cirrhosis
Correct Incorrect Correct answer

Hepatocellular adenoma
Correct Incorrect Correct answer

Previous myocardial infarction
Correct Incorrect Correct answer

Unexplained vaginal bleeding
Correct Incorrect Correct answer

Correct

Incorrect

Question 11 of 63

11. Question

What is the mechanism of action of the progestogen-only injectable implant?

Inhibition of fertilization
Correct Incorrect Correct answer

Inhibition of implantation
Correct Incorrect Correct answer

Inhibition of ovulation
Correct Incorrect Correct answer

Thickening of cervical mucus
Correct Incorrect Correct answer

Thinning of endometrium
Correct Incorrect Correct answer

Correct

Incorrect

Question 12 of 63

12. Question

What is the mechanism of action of the levonorgestrel-releasing intra-uterine system (LNG-IUS)?

Inhibition of fertilization
Correct Incorrect Correct answer

Inhibition of implantation
Correct Incorrect Correct answer

Inhibition of ovulation
Correct Incorrect Correct answer

Thickening of cervical mucus
Correct Incorrect Correct answer

Thinning of endometrium
Correct Incorrect Correct answer

Correct

Incorrect

Question 13 of 63

13. Question

Which of the following should not be recommended for contraception in a patient with epilepsy taking lamotrigine?

Cerazette
Correct Incorrect Correct answer

Copper IUD
Correct Incorrect Correct answer

Microgynon
Correct Incorrect Correct answer

Mirena LNG-IUS
Correct Incorrect Correct answer

Norgeston
Correct Incorrect Correct answer

Correct

Incorrect

Question 14 of 63

14. Question

A 37 year old woman attends for pre-pregnancy counseling as she is planning to try to conceive and has a history of chronic hypertension for which she takes regular medication.Which of the following medications are not contraindicated in pregnancy?

Bendroflumethiazide
Correct Incorrect Correct answer

Candesartan
Correct Incorrect Correct answer

Nifedipine
Correct Incorrect Correct answer

Ramipril
Correct Incorrect Correct answer

Spironolactone
Correct Incorrect Correct answer

Correct

Incorrect

Question 15 of 63

15. Question

Why is clindamycin recommended for the treatment of puerperal sepsis?

Can be used in penicillin-allergic patients
Correct Incorrect Correct answer

Covers Group B Streptococcus
Correct Incorrect Correct answer

Covers MRSA
Correct Incorrect Correct answer

Provides broad-spectrum cover
Correct Incorrect Correct answer

Switches off exotoxin production
Correct Incorrect Correct answer

Correct

Incorrect

Question 16 of 63

16. Question

A 28 year old woman is referred to hospital urgently by her GP at 26 weeks gestation in her second pregnancy.She attended with a two day history of feeling generally unwell with a sore throat and abdominal pain. Her child has also recently been unwell. On examination, she has a widespread maculopapular rash. Her observations are: pulse 130bpm, blood pressure 85/55, temperature 38C, respiratory rate 28, oxygen saturations 94% on RA. On admission to hospital, she is treatment with broad spectrum intravenous antibiotics. Which of the following would be the most appropriate choice of antibiotic?

Amoxicillin
Correct Incorrect Correct answer

Co-amoxiclav
Correct Incorrect Correct answer

Clindamycin
Correct Incorrect Correct answer

Gentamicin
Correct Incorrect Correct answer

Metronidazole
Correct Incorrect Correct answer

Correct

Incorrect

Question 17 of 63

17. Question

A 32-year-old pregnant woman presents with hypertension. Which antihypertensive medication is contraindicated during pregnancy?

Atenolol
Correct Incorrect Correct answer

Hydralazine
Correct Incorrect Correct answer

Lisinopril
Correct Incorrect Correct answer

Methyldopa
Correct Incorrect Correct answer

Nifedipine
Correct Incorrect Correct answer

Correct

Incorrect

Question 18 of 63

18. Question

A patient is prescribed warfarin for deep vein thrombosis. Which vitamin K-containing food should be limited while on warfarin therapy?

Apples
Correct Incorrect Correct answer

Bananas
Correct Incorrect Correct answer

Carrots
Correct Incorrect Correct answer

Oranges
Correct Incorrect Correct answer

Spinach
Correct Incorrect Correct answer

Correct

Incorrect

Question 19 of 63

19. Question

A patient with a history of peptic ulcer disease is prescribed a proton pump inhibitor (PPI). Which of the following is a common side effect of long-term PPI use?

Hyperglycaemia
Correct Incorrect Correct answer

Hyperkalaemia
Correct Incorrect Correct answer

Hypernatraemia
Correct Incorrect Correct answer

Hypomagnesaemia
Correct Incorrect Correct answer

Hyponatraemia
Correct Incorrect Correct answer

Correct

Incorrect

Question 20 of 63

20. Question

Which of the following is a common side effect of tricyclic antidepressants?

Hyperactivity
Correct Incorrect Correct answer

Hypertension
Correct Incorrect Correct answer

Hypoglycaemia
Correct Incorrect Correct answer

Insomnia
Correct Incorrect Correct answer

Weight gain
Correct Incorrect Correct answer

Correct

Incorrect

Question 21 of 63

21. Question

Which of the following medications is a long-acting beta-agonist?

Formoterol
Correct Incorrect Correct answer

Ipratropium
Correct Incorrect Correct answer

Montelukast
Correct Incorrect Correct answer

Salbutamol
Correct Incorrect Correct answer

Theophylline
Correct Incorrect Correct answer

Correct

Incorrect

Question 22 of 63

22. Question

A 60-year-old woman is prescribed bisphosphonate therapy for osteoporosis. Which of the following instructions should be emphasized to prevent adverse effects?

Crush the tablet and mix it with water
Correct Incorrect Correct answer

Stand upright for at least 30 minutes after taking the medication
Correct Incorrect Correct answer

Take the medication just before bedtime
Correct Incorrect Correct answer

Take the medication on an empty stomach
Correct Incorrect Correct answer

Take the medication with a full glass of milk
Correct Incorrect Correct answer

Correct

Incorrect

Question 23 of 63

23. Question

Which of the following electrolyte imbalances is commonly associated with loop diuretic use?

Hypercalcaemia
Correct Incorrect Correct answer

Hyperkalaemia
Correct Incorrect Correct answer

Hypernatraemia
Correct Incorrect Correct answer

Hypokalaemia
Correct Incorrect Correct answer

Hyponatraemia
Correct Incorrect Correct answer

Correct

Incorrect

Question 24 of 63

24. Question

A 28-year-old woman is diagnosed with polycystic ovary syndrome (PCOS) and is prescribed a medication to induce ovulation. Which of the following medications is commonly used for this purpose?

Clomiphene citrate
Correct Incorrect Correct answer

Ethinyl estradiol
Correct Incorrect Correct answer

Leuprolide
Correct Incorrect Correct answer

Metformin
Correct Incorrect Correct answer

Norethindrone
Correct Incorrect Correct answer

Correct

Incorrect

Question 25 of 63

25. Question

Which of the following electrolyte imbalances is a potential side effect of lithium therapy?

Hypercalcaemia
Correct Incorrect Correct answer

Hyperkalaemia
Correct Incorrect Correct answer

Hypernatraemia
Correct Incorrect Correct answer

Hypokalaemia
Correct Incorrect Correct answer

Hyponatraemia
Correct Incorrect Correct answer

Correct

Incorrect

Question 26 of 63

26. Question

A 25-year-old woman is diagnosed with endometriosis and is prescribed a gonadotropin-releasing hormone (GnRH) agonist. Which side effect is commonly associated with long-term use of GnRH agonists?

Hyperkalaemia
Correct Incorrect Correct answer

Hypertension
Correct Incorrect Correct answer

Hypokalaemia
Correct Incorrect Correct answer

Insomnia
Correct Incorrect Correct answer

Osteoporosis
Correct Incorrect Correct answer

Correct

Incorrect

Question 27 of 63

27. Question

A 35-year-old woman is prescribed letrozole for ovulation induction. Which of the following is the primary mechanism of action of letrozole in the treatment of infertility?

Enhancement of progesterone secretion
Correct Incorrect Correct answer

Inhibition of aromatase
Correct Incorrect Correct answer

Inhibition of prolactin release
Correct Incorrect Correct answer

Stimulation of luteinizing hormone (LH)
Correct Incorrect Correct answer

Suppression of follicle-stimulating hormone (FSH)
Correct Incorrect Correct answer

Correct

Incorrect

Question 28 of 63

28. Question

A postmenopausal woman is prescribed hormone replacement therapy (HRT) for the management of menopausal symptoms. Which of the following is commonly included in HRT to reduce the risk endometrial hyperplasia and cancer?

Follicle-stimulating hormone (FSH)
Correct Incorrect Correct answer

Oestrogen and progesterone combined
Correct Incorrect Correct answer

Oestrogen alone
Correct Incorrect Correct answer

Progesterone alone
Correct Incorrect Correct answer

Testosterone
Correct Incorrect Correct answer

Correct

Incorrect

Question 29 of 63

29. Question

A 40-year-old woman with breast cancer is prescribed tamoxifen as part of her adjuvant therapy. What is the primary mechanism of action of tamoxifen in the treatment of breast cancer?

Androgen receptor blockade
Correct Incorrect Correct answer

Aromatase inhibition
Correct Incorrect Correct answer

HER2 receptor inhibition
Correct Incorrect Correct answer

Oestrogen receptor agonism
Correct Incorrect Correct answer

Progesterone receptor antagonism
Correct Incorrect Correct answer

Correct

Incorrect

Question 30 of 63

30. Question

A 28-year-old woman with a history of irregular menstrual cycles is prescribed medroxyprogesterone acetate for the induction of menstruation. What is the mechanism of action of medroxyprogesterone acetate in inducing menstruation?

Inhibition of oestrogen synthesis
Correct Incorrect Correct answer

Stimulation of endometrial proliferation
Correct Incorrect Correct answer

Stimulation of follicle-stimulating hormone (FSH)
Correct Incorrect Correct answer

Suppression of luteinizing hormone (LH)
Correct Incorrect Correct answer

Suppression of prostaglandin production
Correct Incorrect Correct answer

Correct

Incorrect

Question 31 of 63

31. Question

A 35-year-old woman with premature ovarian insufficiency is prescribed raloxifene for the prevention of osteoporosis. What is the primary mechanism of action of raloxifene?

Androgen receptor blockade
Correct Incorrect Correct answer

Inhibition of aromatase
Correct Incorrect Correct answer

Oestrogen receptor antagonism
Correct Incorrect Correct answer

Stimulation of follicle-stimulating hormone (FSH)
Correct Incorrect Correct answer

Suppression of follicle-stimulating hormone (FSH)
Correct Incorrect Correct answer

Correct

Incorrect

Question 32 of 63

32. Question

A 42-year-old woman is prescribed mifepristone for medical termination of pregnancy. What is the primary mechanism of action of mifepristone?

Enhancement of cervical ripening
Correct Incorrect Correct answer

Inhibition of progesterone receptors
Correct Incorrect Correct answer

Inhibition of prostaglandin synthesis
Correct Incorrect Correct answer

Stimulation of uterine contractions
Correct Incorrect Correct answer

Suppression of luteinizing hormone (LH)
Correct Incorrect Correct answer

Correct

Incorrect

Question 33 of 63

33. Question

A 35-year-old woman with heavy menstrual bleeding is prescribed tranexamic acid. What is the primary mechanism of action of tranexamic acid in the treatment of menorrhagia?

Activation of Factor IX
Correct Incorrect Correct answer

Activation of plasminogen
Correct Incorrect Correct answer

Inhibition of fibrinolysis
Correct Incorrect Correct answer

Stimulation of platelet aggregation
Correct Incorrect Correct answer

Vasoconstriction
Correct Incorrect Correct answer

Correct

Incorrect

Question 34 of 63

34. Question

A 42-year-old woman with dysmenorrhea is prescribed a nonsteroidal anti-inflammatory drug (NSAID). Which of the following NSAIDs is commonly used for the management of dysmenorrhea?

Aspirin
Correct Incorrect Correct answer

Celecoxib
Correct Incorrect Correct answer

Ibuprofen
Correct Incorrect Correct answer

Indomethacin
Correct Incorrect Correct answer

Naproxen
Correct Incorrect Correct answer

Correct

Incorrect

Question 35 of 63

35. Question

What is the primary mechanism of action of clindamycin?

Disruption of bacterial DNA replication
Correct Incorrect Correct answer

Inhibition of bacterial cell wall synthesis
Correct Incorrect Correct answer

Inhibition of bacterial folate synthesis
Correct Incorrect Correct answer

Inhibition of bacterial gyrase
Correct Incorrect Correct answer

Inhibition of protein synthesis
Correct Incorrect Correct answer

Correct

Incorrect

Question 36 of 63

36. Question

A 28-year-old woman with a history of recurrent urinary tract infections (UTIs) is prescribed cefalexin. What is the primary mechanism of action of cefalexin?

Disruption of bacterial DNA replication
Correct Incorrect Correct answer

Inhibition of bacterial cell wall synthesis
Correct Incorrect Correct answer

Inhibition of bacterial folate synthesis
Correct Incorrect Correct answer

Inhibition of bacterial gyrase
Correct Incorrect Correct answer

Inhibition of protein synthesis
Correct Incorrect Correct answer

Correct

Incorrect

Question 37 of 63

37. Question

A 28-year-old woman with premenstrual syndrome (PMS) is prescribed sertraline. What type of drug is sertraline?

Monoamine oxidase inhibitor
Correct Incorrect Correct answer

NMDA receptor antagonist
Correct Incorrect Correct answer

Selective serotonin reuptake inhibitor
Correct Incorrect Correct answer

Serotonin–norepinephrine reuptake inhibitor
Correct Incorrect Correct answer

Tricyclic antidepressant
Correct Incorrect Correct answer

Correct

Incorrect

Question 38 of 63

38. Question

Which of the following is a cytochrome P450 inducer?

Fluconazole
Correct Incorrect Correct answer

Isoniazid
Correct Incorrect Correct answer

Metronidazole
Correct Incorrect Correct answer

Rifampicin
Correct Incorrect Correct answer

Sodium valproate
Correct Incorrect Correct answer

Correct

Incorrect

Question 39 of 63

39. Question

Which of the following is a cytochrome P450 inducer?

Carbamazepine
Correct Incorrect Correct answer

Gliclazide
Correct Incorrect Correct answer

Phenytoin
Correct Incorrect Correct answer

Rifampicin
Correct Incorrect Correct answer

Sulfasalazine
Correct Incorrect Correct answer

Correct

Incorrect

Question 40 of 63

40. Question

Which of the following drugs undergoes significant first-pass metabolism in the gut?

Benzylpenicillin
Correct Incorrect Correct answer

Glyceryl trinitrate
Correct Incorrect Correct answer

Lignocaine
Correct Incorrect Correct answer

Morphine
Correct Incorrect Correct answer

Propranolol
Correct Incorrect Correct answer

Correct

Incorrect

Question 41 of 63

41. Question

Which of the following drugs undergoes minimal first-pass metabolism?

5-fluorouracil
Correct Incorrect Correct answer

Diazepam
Correct Incorrect Correct answer

Isosorbide mononitrate
Correct Incorrect Correct answer

Mercaptopurine
Correct Incorrect Correct answer

Morphine
Correct Incorrect Correct answer

Correct

Incorrect

Question 42 of 63

42. Question

What is the mechanism of action of labetalol?

ACE inhibitor
Correct Incorrect Correct answer

Angiotensin receptor blocker
Correct Incorrect Correct answer

Beta blocker
Correct Incorrect Correct answer

Calcium channel blocker
Correct Incorrect Correct answer

Loop diuretic
Correct Incorrect Correct answer

Correct

Incorrect

Question 43 of 63

43. Question

What is the mechanism of action of nifedipine?

ACE inhibitor
Correct Incorrect Correct answer

Angiotensin receptor blocker
Correct Incorrect Correct answer

Beta blocker
Correct Incorrect Correct answer

Calcium channel blocker
Correct Incorrect Correct answer

Loop diuretic
Correct Incorrect Correct answer

Correct

Incorrect

Question 44 of 63

44. Question

What is the mechanism of action of lisinopril?

ACE inhibitor
Correct Incorrect Correct answer

Angiotensin receptor blocker
Correct Incorrect Correct answer

Beta blocker
Correct Incorrect Correct answer

Calcium channel blocker
Correct Incorrect Correct answer

Loop diuretic
Correct Incorrect Correct answer

Correct

Incorrect

Question 45 of 63

45. Question

What is the mechanism of action of candesartan?

ACE inhibitor
Correct Incorrect Correct answer

Angiotensin receptor blocker
Correct Incorrect Correct answer

Beta blocker
Correct Incorrect Correct answer

Calcium channel blocker
Correct Incorrect Correct answer

Loop diuretic
Correct Incorrect Correct answer

Correct

Incorrect

Question 46 of 63

46. Question

What is the mechanism of action of frusemide?

ACE inhibitor
Correct Incorrect Correct answer

Angiotensin receptor blocker
Correct Incorrect Correct answer

Beta blocker
Correct Incorrect Correct answer

Calcium channel blocker
Correct Incorrect Correct answer

Loop diuretic
Correct Incorrect Correct answer

Correct

Incorrect

Question 47 of 63

47. Question

What is the mechanism of action of warfarin?

Activation of antithrombin III
Correct Incorrect Correct answer

Direct inhibition of Factor Xa
Correct Incorrect Correct answer

Direct inhibition of fibrinogen
Correct Incorrect Correct answer

Direct thrombin inhibition
Correct Incorrect Correct answer

Inhibition of Vitamin K epoxide reductase
Correct Incorrect Correct answer

Correct

Incorrect

Question 48 of 63

48. Question

What is the mechanism of action of unfractionated heparin?

Activation of antithrombin III
Correct Incorrect Correct answer

Direct inhibition of Factor Xa
Correct Incorrect Correct answer

Direct inhibition of fibrinogen
Correct Incorrect Correct answer

Direct thrombin inhibition
Correct Incorrect Correct answer

Inhibition of Vitamin K epoxide reductase
Correct Incorrect Correct answer

Correct

Incorrect

Question 49 of 63

49. Question

What is the mechanism of action of low molecular weight heparin?

Activation of antithrombin III
Correct Incorrect Correct answer

Direct inhibition of Factor Xa
Correct Incorrect Correct answer

Direct inhibition of fibrinogen
Correct Incorrect Correct answer

Direct thrombin inhibition
Correct Incorrect Correct answer

Inhibition of Vitamin K epoxide reductase
Correct Incorrect Correct answer

Correct

Incorrect

Question 50 of 63

50. Question

What is the mechanism of action of dabigatran?

Activation of antithrombin III
Correct Incorrect Correct answer

Direct inhibition of Factor Xa
Correct Incorrect Correct answer

Direct inhibition of fibrinogen
Correct Incorrect Correct answer

Direct thrombin inhibition
Correct Incorrect Correct answer

Inhibition of Vitamin K epoxide reductase
Correct Incorrect Correct answer

Correct

Incorrect

Question 51 of 63

51. Question

What is the mechanism of action of apixaban?

Activation of antithrombin III
Correct Incorrect Correct answer

Direct inhibition of Factor Xa
Correct Incorrect Correct answer

Direct inhibition of fibrinogen
Correct Incorrect Correct answer

Direct thrombin inhibition
Correct Incorrect Correct answer

Inhibition of Vitamin K epoxide reductase
Correct Incorrect Correct answer

Correct

Incorrect

Question 52 of 63

52. Question

Which of the following is used to treat nocturia?

Desmopressin
Correct Incorrect Correct answer

Duloxetine
Correct Incorrect Correct answer

Fluoxetine
Correct Incorrect Correct answer

Mirabegron
Correct Incorrect Correct answer

Tolterodine
Correct Incorrect Correct answer

Correct

Incorrect

Question 53 of 63

53. Question

Which of the following is used to treat stress urinary incontinence?

Desmopressin
Correct Incorrect Correct answer

Duloxetine
Correct Incorrect Correct answer

Fluoxetine
Correct Incorrect Correct answer

Mirabegron
Correct Incorrect Correct answer

Tolterodine
Correct Incorrect Correct answer

Correct

Incorrect

Question 54 of 63

54. Question

Which of the following is an antimuscarinic agent used as a first line treatment for overactive bladder?

Desmopressin
Correct Incorrect Correct answer

Duloxetine
Correct Incorrect Correct answer

Fluoxetine
Correct Incorrect Correct answer

Mirabegron
Correct Incorrect Correct answer

Tolterodine
Correct Incorrect Correct answer

Correct

Incorrect

Question 55 of 63

55. Question

A 36 year old woman has just delivered her second child by elective Caesarean section with spinal anaesthetic. When should low molecular weight heparin prophylaxis be started?

After 4 hours
Correct Incorrect Correct answer

After 6 hours
Correct Incorrect Correct answer

After 12 hours
Correct Incorrect Correct answer

After 24 hours
Correct Incorrect Correct answer

Low molecular weight heparin prophylaxis is not required
Correct Incorrect Correct answer

Correct

Incorrect

Question 56 of 63

56. Question

A 38 year old woman has delivered her second child by elective Caesarean section. How long is low molecular weight heparin prophylaxis required for?

7 days
Correct Incorrect Correct answer

10 days
Correct Incorrect Correct answer

14 days
Correct Incorrect Correct answer

6 weeks
Correct Incorrect Correct answer

Not required
Correct Incorrect Correct answer

Correct

Incorrect

Question 57 of 63

57. Question

A 28 year old woman has delivered by elective Caesarean section. What is the most appropriate thromboprophylaxis?

7 days of low molecular weight heparin prophylaxis
Correct Incorrect Correct answer

10 days of low molecular weight heparin prophylaxis
Correct Incorrect Correct answer

6 weeks of low molecular weight heparin prophylaxis
Correct Incorrect Correct answer

Early mobilisation & avoidance of dehydration
Correct Incorrect Correct answer

No VTE prophylaxis is required
Correct Incorrect Correct answer

Correct

Incorrect

Question 58 of 63

58. Question

A 23 year old woman has a spontaneous vaginal delivery of her first child at term. She had a booking BMI of 47. What is the most appropriate thromboprophylaxis?

7 days of low molecular weight heparin prophylaxis
Correct Incorrect Correct answer

10 days of low molecular weight heparin prophylaxis
Correct Incorrect Correct answer

6 weeks of low molecular weight heparin prophylaxis
Correct Incorrect Correct answer

Early mobilisation & avoidance of dehydration
Correct Incorrect Correct answer

Anti-thromboembolism stockings
Correct Incorrect Correct answer

Correct

Incorrect

Question 59 of 63

59. Question

A 37 year old woman has just delivered her second child. She had been taking prophylactic low molecular weight heparin during her pregnancy because of a history of DVT in her pregnancy. How long should low molecular weight heparin prophylaxis be continued postnatally?

7 days
Correct Incorrect Correct answer

10 days
Correct Incorrect Correct answer

2 weeks
Correct Incorrect Correct answer

4 weeks
Correct Incorrect Correct answer

6 weeks
Correct Incorrect Correct answer

Correct

Incorrect

Question 60 of 63

60. Question

A 20 year old woman attends the maternal medicine pre-pregnancy counselling service. She has a history of primary generalized epilepsy for which she has been on long term medication. Which of the following is associated with the highest risk of congenital malformations?

Lamotrigine
Correct Incorrect Correct answer

Leviracetam
Correct Incorrect Correct answer

Carbamazepine
Correct Incorrect Correct answer

Phenytoin
Correct Incorrect Correct answer

Topiramate
Correct Incorrect Correct answer

Correct

Incorrect

Question 61 of 63

61. Question

A 20 year old woman attends the maternal medicine pre-pregnancy counselling service. She has a history of primary generalized epilepsy for which she has been on long term medication. Which of the following is associated with the lowest risk of congenital malformations?

Carbamazepine
Correct Incorrect Correct answer

Leviracetam
Correct Incorrect Correct answer

Phenobarbital
Correct Incorrect Correct answer

Phenytoin
Correct Incorrect Correct answer

Topiramate
Correct Incorrect Correct answer

Correct

Incorrect

Question 62 of 63

62. Question

A 20 year old woman attends the maternal medicine pre-pregnancy counselling service. She has a history of primary generalized epilepsy for which she has been on long term sodium valproate. What is the incidence of congenital malformation in babies exposed to sodium valproate in utero?

5%
Correct Incorrect Correct answer

10%
Correct Incorrect Correct answer

15%
Correct Incorrect Correct answer

20%
Correct Incorrect Correct answer

25%
Correct Incorrect Correct answer

Correct

Incorrect

Question 63 of 63

63. Question

A 20 year old woman attends the maternal medicine pre-pregnancy counselling service. She has a history of primary generalized epilepsy for which she has been on long term sodium valproate. What is the incidence of neurodevelopmental disorders in babies exposed to sodium valproate in utero?

5%
Correct Incorrect Correct answer

15%
Correct Incorrect Correct answer

25%
Correct Incorrect Correct answer

35%
Correct Incorrect Correct answer

45%
Correct Incorrect Correct answer

Correct

Incorrect