New SBA and EMQ questions on Hepatitis B in Pregnancy

A 29 year old primiparous woman has antenatal screening for Hepatitis B at booking at 11 weeks gestation and has a positive result with positive HBsAg.  She has confirmatory serology testing which shows:

• HBsAg positive
• Anti-HBs negative
• HBeAg positive
• Anti-HBe negative
• Anti-Hbc IgM negative
• Anti-Hbc IgG positive
• HBV DNA 270,867 IU/ml

What is the most appropriate management?

A 29-year-old pregnant woman is found to be hepatitis B surface antigen (HBsAg) positive at booking. Further serological testing is performed. Which of the following serological profiles is associated with the highest risk of vertical transmission of hepatitis B virus to the infant?

A 29 year old primiparous woman is diagnosed with chronic hepatitis B infection during pregnancy with low HBV viral load <50 IU.ml. She has an uncomplicated vaginal birth at 38 weeks gestation with birthweight of 3.4kg. What is the most appropriate neonatal management?

A 29 year old primiparous woman is diagnosed with chronic hepatitis B infection during pregnancy with low HBV viral load <50 IU.ml. She presents in spontaneous preterm labour at 30 weeks gestation and has an uncomplicated vaginal birth with birthweight of 1.5kg. What is the most appropriate neonatal management?